삼릉 에탄올추출물의 in vitro 피부 미백 유효성

Effectiveness of Scirpi rhizoma Ethanol Extract on Skin Whitening Using in vitro Test

저자명 고주영, 김영철

문서유형 학술논문

참고문헌 32건

인용된횟수 1건

학술지 환경독성보건학회지 제25권 제1호 통권 제68호 (2010년 3월) pp.69-77 1226-9158 KCI 

발행정보 환경독성보건학회 |2010년 |한국 |한국어

초록

The purpose of this study is to evaluate the effectiveness of Scirpi rhizoma ethanol extract (SREE) on skin whitening using in vitro test. In the anti oxidative activities, it was found that SREE contains 38.9㎎/g of polyphenol and 74.5 ㎎/g of flavonoid in total. In the electron donating ability, SREE showed a dose-dependent response, showing a high antioxidative capacity of 86.1% at 1000 ppm. It was found that the maximum permissible level of SREE to Melan-a cells was over 200 ppm, showing a quite low toxicity of SREE against Melan-a cells. Both in the inhibitory measurement for tyrosinase activity and melanogenesis using Melan-a cells, SREE presented a dose-dependent response with excellent efficacy.