苦蔘 추출물을 함유한 화장수의 여드름에 대한 효과

Effect of Sophorae Radix-Skin Lotion on Acne

저자명 백상철, 조은희, 맹드게렐, 박민철

문서유형 학술논문

참고문헌 35건

학술지 한방안이비인후피부과학회지 제24권 제1호 통권44호 (2011년 4월) pp.111-120 1738-6640 KCI 

발행정보 대한한방안이비인후피부과학회 |2011년 |한국 |한국어

초록

Background & Objective : Sophorae Radix has been known as an useful plant with anti-inflammatory and anti-bacterial activity. Therefore, Sophorae Radix is expected to mitigate and prevent acne by inhibiting the activity of the sebaceous glands and acne bacterium. To evaluate anti-inflammation effect of Sophorae Radix, we applied Sophorae Radix-skin lotion on the patients with acne. Methods : The Sophorae Radix-skin lotion was prepared by dissolving 1% ethanol extract of Sophorae Radix in skin lotion vehicle and treated 2 times everyday for 4 weeks on faces. Follow-up was performed with Janus facial analysis system. Results : Sophorae Radix-skin lotion reduced sebum and porphyrin. However, the Sophorae Radix-skin lotion didn't significantly reduced sebum and porphyrin compared with skin lotion vehicle control group. Conclusion : These results showed that the Sophorae Radix-skin lotion could be used as a pharmaceutical material with anti-inflammatory effects by reducing sebum and porphyrin in acne patient with further clinical research.